BIOS 531. Clinical Epidemiology. 3 Hours.

Semester course; 3 lecture hours. 3 credits. This course is intended primarily for clinicians. Permission of the course coordinator is required for others interested in registering. Epidemiological concepts necessary for evidence based studies of medicine. Specific topics will include: cause and effect criteria, demographic rates, measures of association or effect, study designs, decision trees, meta-analysis, evaluation of the literature, sources of data, reliability and validity, bias, confounding and effect modification, screening and diagnostic tests, sensitivity, specificity, false positives, false negatives, applications of the above to diagnosis and treatment, treatment efficacy and improved patient care.