The Inflammation/ Asthma Group consists of Drs. Spiegel, Diegelmann, Kordula, Milstien, and Larner. The members of this group are studying biochemical, physiological, and immunological mechanisms in the inflammatory response. The expertise of this group includes macrophage biology, the biochemistry of the extracellular matrix, lipid signaling, and vascular physiology. Together, these investigators are elucidating the cellular and molecular mechanisms of inflammation in hopes of modulating this process to control asthma, periodontal disease, and allergy.