COVID-19 Technologies

These COVID-19 related technologies include new inventions that are directly targeted to COVID-19, as well as existing inventions that could be used or modified to fight COVID-19. VCU Innovation Gateway is offering free ready-to-execute licenses to hospitals and industry partners to use and/or manufacture these inventions and related products in the COVID-19 pandemic. VCU Innovation Gateway endorses and it is licensing technologies applied to COVID-19 under the terms of the COVID-19 Technology Access Framework.

To request a free license to one of these technologies, contact ott@vcu.edu or click on the direct download link (if available) for that technology.

20-082F - Novel COVID19 Treatment 
This technology consists of a novel synthetic, small molecule that selectively interferes with the SARS-CoV-2 spike glycoproteins binding to heparan sulfate receptors present on the human host cell's surface. This compound could be used to limit the virus-to-cell fusion of SARS-CoV-2 with human cells, which makes this compound a potential treatment for COVID19 and other enveloped viruses.

20-034 - SARS-CoV-2 Vaccination Delivery System 
This technology utilizes a microneedle delivery system composed of FDA approved materials. The microneedle system is coupled with a novel lipid nanoparticle hydrogel that stabilizes an accompanying vaccine and allows it to be distributed and self-administered by the recipient, limiting the strain on the medical system. 

20-030 - Novel SARS-CoV-2 Treatment
This technology consists of a novel peptide which binds with high affinity to the SD1 segment of the SARS-CoV-2 spike protein, thus mimicking its attachment to ACE2. This could be used to help slow and limit the transmission of the virus and help develop novel targets for SARS-CoV-2. 

18-056 Anti-microbial Filters
This technology is an wire mesh with iron oxide nanowires. When electrified with a low voltage current, the mesh is able to inactive microbes through electroporation and joule heating effects. This technology has been designed for HVAC systems and may be adaptable to industrial cleaning systems or positive pressure respirators.

18-019 Synthesizing Hydroxychloroquine
A high-yielding semi-continuous flow method for producing hydroxychloroquine (HCQ), a drug that may be useful as a treatment for COVID-19.

17-075F Capillary-Based Dry Powder Inhaler
This technology improves dry powder inhalers and is compatible with mechanical ventilation.

12-063 Richmond Agitation-Sedation Scale (RASS)
A quick and reliable method to evaluate sedation (e.g., during mechanical ventilation). RASS is an excellent tool to include in treatment guidelines due to its familiarity to many healthcare providers and overall simplicity.

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