Document Type

Article

Original Publication Date

2015

Journal/Book/Conference Title

Bone & Joint Research

Volume

4

DOI of Original Publication

10.1302/2046-3758.43.2000337

Comments

Originally published at http://dx.doi.org/10.1302/2046-3758.43.2000337

Date of Submission

May 2016

Abstract

Objectives The clinical utility of routine cross sectional imaging of the abdomen and pelvis in the screening and surveillance of patients with primary soft-tissue sarcoma of the extremities for metastatic disease is controversial, based on its questionable yield paired with concerns regarding the risks of radiation exposure, cost, and morbidity resulting from false positive findings.

Methods Through retrospective review of 140 patients of all ages (mean 53 years; 2 to 88) diagnosed with soft-tissue sarcoma of the extremity with a mean follow-up of 33 months (0 to 291), we sought to determine the overall incidence of isolated abdominopelvic metastases, their temporal relationship to chest involvement, the rate of false positives, and to identify disparate rates of metastases based on sarcoma subtype.

Results A total of four patients (2.9%) exhibited isolated abdominopelvic metastatic disease during the surveillance period. In all cases of concomitant chest and abdominopelvic disease, chest involvement preceded abominopelvic involvement. There was a significant false positive rate requiring invasive workup.

Conclusions In the setting of a relative paucity of evidence concerning a rare disease process and in difference to recently published investigations, we add a clinical cohort not supportive of routine cross sectional imaging of the abdomen and pelvis.

Rights

Copyright ©2015 The British Editorial Society of Bone & Joint Surgery

Is Part Of

VCU Orthopaedic Surgery Publications

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