The research in our lab is focused on drug discovery/development for CNS disorders.
Three major directions are being undertaken to development effective small molecules as disease-modifying agents and chemical probes:
1) Bivalent compounds for Alzheimer's disease;
2) Curcumin/melatonin hybrids as neuroprotectants for Alzheimer's disease; and
3) Novel NLRP3 inflammasome inhibitors for inflammatory disorders including Alzheimer's disease, multiple sclerosis, traumatic brain injury, and acute myocardial infarction.