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Institute for Structural Biology, Drug Discovery and Development

Dr. Yana Cen Receives Grant from the National Science Foundation (Chemistry of Life Processes)

September 27, 2019

The grant title is CAREER:  Allosteric Activating of SIRT6 by DNA and the project period is 09/01/2019 - 08/31/2024. This study seeks to elucidate how the regulation of SIRT6 activity takes place in cells and to suggest possible strategies for effective SIRT6 activation. The concurrent aim is to provide a broadly accessible research experience for a large number of students across multiple academic levels. The comprehensive plan includes the mentoring of undergraduates, graduates and PharmD students as well as an outreach program offered to high school AP biology students. A PI-graduate student working group is to be established to develop and implement new guidelines for training in the interdisciplinary field of chemical biology. 

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