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Institute for Structural Biology, Drug Discovery and Development

H. Tonie Wright

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Professor Emeritus
(804) 828-6139

Areas of Focus

  • interactions of biological macromolecules and enzymatic mechanisms at the atomic level
  • interactions of the Alzheimer’s amyloid peptide Aβ in its different forms with inflammatory proteins and the effects of these interactions on reactive oxygen release from activated rat microglia (from Carmen Sato-Bigbee)
  • interactions of synthetic polyanionic molecules with proteins of the thrombosis/fibrinolysis pathway as possible replacement anticoagulants for heparin
  • structural studies of transcriptional regulators of oxidative stress response genes in bacteria

Department of Biochemistry and Molecular Biology directory profile

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