Reproductive Biology Research

High-Risk Pregnancy

Led by Scott Walsh, Ph.D. and Jerome Strauss, III, M.D., Ph.D., this area of OB/GYN research is dedicated to the advancement of maternal-fetal medicine and improving care for high-risk pregnancies.

Current Projects

  • Genetic variants associated with preterm premature rupture of membranes and cervical insufficiency (PI: Dr. Strauss)
  • Environmental factors contributing to preterm birth, such as the vaginal microbiome (PI: Dr. Strauss)
  • The immunological role of neutrophils that infiltrate blood vessels of preeclamptic women and their pregnancy-specific expression of protease-activated receptor 1 as a cause of vascular dysfunction, inflammation and enhanced vascular reactivity in preeclampsia (PI: Dr. Walsh)
  • Identifying a unique lipid profile in maternal blood or urine early in pregnancy that will predict women who will later develop preeclampsia or other pregnancy complications (PI: Dr. Walsh)
  • Why African Americans have higher incidences of premature birth and low-birth-weight infants than other ethnic groups (PI: Dr. Walsh)

Infertility

Dr. Strauss and Maria Teves, Ph.D., study female and male infertility through the lenses of genetics and molecular cell biology.

Current Projects

  • Genetic variants associated with preterm premature rupture of membranes and cervical insufficiency (PI: Dr. Strauss)
  • Environmental factors contributing to preterm birth, such as the vaginal microbiome (PI: Dr. Strauss)
  • The immunological role of neutrophils that infiltrate blood vessels of preeclamptic women and their pregnancy-specific expression of protease-activated receptor 1 as a cause of vascular dysfunction, inflammation and enhanced vascular reactivity in preeclampsia (PI: Dr. Walsh)
  • Identifying a unique lipid profile in maternal blood or urine early in pregnancy that will predict women who will later develop preeclampsia or other pregnancy complications (PI: Dr. Walsh)
  • Why African Americans have higher incidences of premature birth and low-birth-weight infants than other ethnic groups (PI: Dr. Walsh)

Ovarian Function

Dr. Strauss is investigating the role of estrogens in angiogenesis, with a focus on hydroxyestradiol metabolites and catechol estrogens and their pro- and anti-angiogenic activities in regulating follicular growth and corpus luteum function.

 

Maria E. Teves, Ph.D. [View Image]

Maria E. Teves, Ph.D.

Maria E. Teves, Ph.D. [View Image]

Maria E. Teves, Ph.D.

Department of OB/GYN

Assistant Professor

Email: maria.teves@vcuhealth.org

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Scott W. Walsh, Ph.D. [View Image]

Scott W. Walsh, Ph.D.

Scott W. Walsh, Ph.D. [View Image]

Scott W. Walsh, Ph.D.

Department of OB/GYN

Division Head, Reproductive Biology Research
Professor

Email: scott.walsh@vcuhealth.org

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