Document Type

Article

Original Publication Date

2015

Journal/Book/Conference Title

World Journal of Orthopedics

Volume

6

Issue

8

DOI of Original Publication

10.5312/wjo.v6.i8.567

Comments

Originally published at http://dx.doi.org/10.5312/wjo.v6.i8.567

Date of Submission

November 2015

Abstract

The drastic changes in body composition following spinal cord injury (SCI) have been shown to play a significant role in cardiovascular and metabolic health. The pattern of storage and distribution of different types of adipose tissue may impact metabolic health variables similar to carbohydrate, lipid and bone metabolism. The use of magnetic resonance imaging provides insights on the interplay among different regional adipose tissue compartments and their role in developing chronic diseases. Regional adipose tissue can be either distributed centrally or peripherally into subcutaneous and ectopic sites. The primary ectopic adipose tissue sites are visceral, intramuscular and bone marrow. Dysfunction in the central nervous system following SCI impacts the pattern of distribution of adiposity especially between tetraplegia and paraplegia. The current editorial is focused primarily on introducing different types of adipose tissue and establishing scientific basis to develop appropriate dietary, rehabilitation or pharmaceutical interventions to manage the negative consequences of increasing adiposity after SCI. We have also summarized the clinical implications and future recommendations relevant to study adiposity after SCI.

Rights

Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.

Is Part Of

VCU Physical Medicine and Rehabilitation Publications

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