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S. Patrick Nana-Sinkam, M.D., F.C.C.P.

Massey Cancer Center research program membership

Cancer Prevention and Control

Department affiliations

Professor, Division of Pulmonary Disease and Critical Care Medicine (Chair), Department of Internal Medicine, School of Medicine

Endowed and distinguished chair or professorship

Linda Grandis Blatt Endowed Chair in Cancer Research

Education

MD, Wake Forest University (1996)

Awards and honors

Excellence in Teaching Award, 2015, Ohio State

Research description

Focus/Project 1: One goal of our laboratory is to elucidate the role of recently discovered non-coding RNAs in lung tumor development and progression. We are approaching this through analysis in primary human lung cancers and peripheral blood complemented by allied studies that examine the effects of selective microRNA targeting on cancer cell phenotype. Focus/Project 2: Our laboratory has been very interested in increasing our understanding of the molecular heterogeneity that exist in lung cancer by utilizing genomic and proteomic platforms coupled with computational modeling. By applying systems biology to human samples, we may identify perturbations of key biological networks that are critical to tumor development and progression. Focus/Project 3: Examining the role of extracellular vesicles as drivers of cancer initiation and progression Focus/Project 4: We are currently pursuing in collaboration with nanoengineering novel platforms for the non-invasive detection and therapeutic delivery of miRNA in lung disease

Disease focus of research

Respiratory/lung

Research keywords

Bioinformatics,Biomarkers,Cancer cell biology,Cancer diagnostics,Cancer disparities,Epigenetics,Genomics,Precision medicine,Prevention/population health,Screening,Translational science

Published research (during tenure as a Massey Cancer Center member)

Search In PubMed

Contact information

Email: patrick.nana-sinkam@vcuhealth.org

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