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David A. Gewirtz, Ph.D.

Massey Cancer Center research program membership

Developmental Therapeutics

Department affiliations

Professor, Department of Pharmacology and Toxicology, School of Medicine


PhD, Icahn School of Medicine at Mount Sinai (1978)

Research description

Research in the Gewirtz laboratory is focused on the autophagy and senescence responses to chemotherapy and radiation in various tumor cell models. Our overall goals are to identify strategies for sensitization of malignancies to standard of care therapies via inhibition of cytoprotective autophagy and/or exposure to senolytics of senescent tumor cells.

Disease focus of research

Breast, Prostate, Head & neck, Respiratory/lung

Research keywords

Autophagy,Cancer therapy,Cancer therapy resistance,Cancer therapy toxicities,Radiotherapy,Senescence

Published research (during tenure as a Massey Cancer Center member)

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Contact information


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