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VCU Massey Cancer Center


Cardio-oncologist first to demonstrate that MRI stress testing can identify patients at risk of a heart attack joins Massey as physician-researcher

Hundley studies the effect of cancer treatment on cardiovascular health

Cardio-oncologist William Gregory Hundley, M.D., who was recently appointed the inaugural director of the Pauley Heart Center at VCU Health, has joined VCU Massey Cancer Center as a member of its Cancer Prevention and Control research program and will serve on Massey’s Senior Advisory Committee.

Hundley studies the effects of chemotherapy and radiation therapy on cardiovascular health as a means to reduce heart failure and more effectively personalize treatment options for cancer patients.

“My work is focused on understanding the causes of heart failure; specifically, how cancer treatments impact heart health,” said Hundley, who is also a professor in the Division of Cardiology of the Department of Internal Medicine at the VCU School of Medicine and will serve as the clinical director of noninvasive cardiology at VCU Medical Center. “Ultimately, I hope that my research will help to better prevent and treat heart and vascular disease in those treated for cancer as well as other more common conditions, including: high blood pressure, diabetes, coronary artery disease and heart failure.”

“Dr. Hundley is a recognized leader in studying the cardiac complications of cancer therapies,” said Gordon D. Ginder, M.D., director of VCU Massey Cancer Center. “He had established collaborations with Massey researchers prior to joining VCU, and now that he is on faculty here, we anticipate and look forward to building more and deeper research connections among our cancer and heart specialists to the benefit of our patients at Massey and Pauley, as well as in Virginia and nationally.”

With the help of a newly established, state-of-the-art Cardiac Imaging Suite at VCU Health, Hundley will support personalized cardio-oncology evaluation, diagnosis and treatment. He was the first person in the world to demonstrate that magnetic resonance imaging (MRI) stress testing can identify patients at risk of a heart attack.

Over the last two decades, Hundley has participated in $71 million in grant funding from the National Institutes of Health to conduct his research. He is currently the principal investigator on a $4.5 million randomized clinical trial funded by the National Heart, Lung and Blood Institute testing statin therapy (cholesterol-reducing medication) as a means of preventing chemotherapy-induced heart injury in triple negative breast cancer patients. He was awarded the National Institute of Health’s “Clinical Associate Physician Award” in 1999.

Additionally, he is the principal investigator on two grants funded by the National Cancer Institute. The first is a clinical study of 1,000 women to identify risk factors of cardiac and cognitive dysfunction caused by breast cancer treatment. The second, completed earlier this year, was a $2.5 million grant for the development of novel imaging methods that can identify early signs of heart damage caused by chemotherapy or radiation to prevent or minimize permanent cardiovascular damage.

Hundley comes to VCU from Wake Forest School of Medicine where he served in several roles over the past 22 years, most recently as the medical director of the Reynolds Tower Cardiovascular Imaging Facility, focusing on preventive heart care for cancer patients undergoing chemotherapy and radiation.

Born in Richmond, Hundley earned his bachelor’s degree from the College of William & Mary and his medical degree from the VCU School of Medicine. He completed his postdoctoral internship, residency and fellowship at the University of Texas Southwestern Medical Center and Parkland Memorial Hospital and then became a tenured full professor at the Wake Forest School of Medicine.

Hundley has published more than 200 articles in peer-reviewed journals, including Circulation, Diabetes Care, European Heart Journal and JAMA, and has authored more than 150 abstracts, review articles and position papers. He is an associate editor for Cardiology Today and Circulation, and serves on the editorial board for five peer-reviewed journals as well.

Certified by the American Board of Internal Medicine in cardiovascular disease and the National Board of Echocardiography, Hundley is the founder of MRI Cardiac Services, Inc., Follow Your Heart, LLC, and Albus Imaging, LLC. He currently serves as a member of the American College of Cardiology Integrated Learning Committee, Cardiovascular Imaging Committee and the American College of Cardiology Imaging Network. He is a fellow of the American College of Cardiology and the American College of Physicians; a member of the Clinical Cardiology Council and CV Radiology Council of the American Heart Association; and a member of the Society of Cardiovascular Magnetic Resonance in Medicine.

Written by: Jenny Owen

Posted on: July 24, 2018

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