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Brian Wattenberg, Ph.D.

Massey Cancer Center research program membership

Cancer Cell Signaling

Department affiliations

Professor, Department of Biochemistry and Molecular Biology, School of Medicine


PhD, Washington University (1981)

Research description

We are studying how levels of sphingolipids are regulated. Sphingolipids are a class of lipids that have diverse functions in biology, including structural roles in membranes and as signaling molecules. Some members of this family of lipids promote proliferation and some promote cell death, both processes crucial to cancer biology. We hope that through a detailed understanding of how these levels are regulated, we will be able to design therapeutic approaches that alter metabolism to promote the death of cancer cells.

Disease focus of research

Brain & nervous system

Research keywords

Apoptosis,Cancer cell biology,Lipid signaling,Proteomics

Published research (during tenure as a Massey Cancer Center member)

Search In PubMed

Contact information


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