Can Senkal, Ph.D.
Massey Cancer Center research program membership
Cancer Cell Signaling
Assistant Professor, Department of Biochemistry and Molecular Biology, School of Medicine
PhD, The Medical University of South Carolina (2008)
We are interested in the roles and regulation of sphingolipids in cancer biologies, such as tumor initiation, response to therapy, and metastasis. Specifically, we want to identify how ceramide generation by ceramide synthase enzymes is regulated in cancer versus in normal cells. We are also interested in identifying the molecular mechanisms of how ceramide exerts its anti-cancer signaling properties.
Disease focus of research
Breast, Colorectal, Pancreatic, Respiratory/lung
Apoptosis,Autophagy,Cancer cell biology,Cancer therapy resistance,Cell signaling,Inflammation,Lipid signaling,Metabolism,Proteomics,Signal transduction
Published research (during tenure as a Massey Cancer Center member)
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