Valentina Robila, M.D., Ph.D.
Massey Cancer Center research program membership
Cancer Molecular Genetics
Assistant Professor, Department of Pathology, School of Medicine
PhD, University of Virginia (2016)
MD, University of Iasi, Romania (1998)
Expanding on recently published work in collaboration with Paula Bos, Ph.D. (VCU) and investigating tumor infiltrating lymphocytes in association with breast carcinoma, we proposed new projects aimed at investigating the role of tumor microenvironment in the progression from ductal carcinoma in situ to invasive carcinoma. These will include the immune mechanisms responsible for DCIS progression in the mouse model, as well as characterization of the immune infiltrate associated with human noninvasive breast lesions and their correlation with outcome. The goal is to characterize early immune responses to neoplastic transformation and hopefully identify immune phenotypes that are associated with progression that can be used as biomarkers for risk stratification. Several studies are underway regarding correlation of architectural patterns of lung adenocarcinoma and molecular signatures. Of special interest are carcinomas with mucinous component, a newly described micropapillary pattern (the filigree pattern), and the participation in research associated with renal cell carcinoma.
Disease focus of research
Breast, Respiratory - Lung, Prostate
Published research (during tenure as a Massey Cancer Center member)
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